Skoloseme - a most wretched poison feared and coveted by the Kindred in equal measure for its ability to kill the even already-dead. Any container which holds it, even glass, weeps filth and eventually finds itself covered in a layer of stinking grease. The poison itself, a milky white substance, causes a [huge chunk of aggravated damage/save vs death] upon entry into the body of a Kindred, as their spine rebels against them; of course, it's a certain, agonizing death for any human unfortunate enough to even touch it.
The etymological origin of the name Skoloseme is much debated among vampirekind. The vampiric scribe Uglubathr wrote that the name was a vile pun based on its creation and appearance, as it was brewed with the seminal emissions of centipedes in an unclean skull for a month and a night; a recipe revealed to them during their visits to certain abandoned Mithraic sites in the south of the continent. The Jesuit missionary Rinieri Mazelo (widely regarded by modern Kindred scholars as a pawn of his grandsire the Shivan Mater) violently contests this suggested origin as a "deluded distortion of certain Oriental rituals, typical for the seizures of those of Mala Cavilla humour" but provides no real alternative as to its origins.
The historian and chronicler Glaude takes a completely different tack. He suggests that the name is a scribal error for the earlier and more accurate name of skotoseme, or simply "suicide poison"; a name the substance earned when the vampiric princess Aylin killed herself and much of her court by pouring the poison into her eyes, during the Kindred civil war in Constantinople.

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